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Welcome to The EMBO Journal

We are pleased to announce our brand new FOCUS on Quality Control. This collection of eight review articles highlights different aspects of cellular quality control and their relevance for human diseases. It includes reviews on mitochondrial and ER quality control, protein folding and degradation, as well as quality control in RNA and DNA metabolism.
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Volume 27, Number 14
(23 July 2008)
ISSN 0261 - 4189
Online ISSN 1460 - 2075
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In this issue
Mre11–Rad50–Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity
The MRN complex promotes ATM activity by unknown mechanisms. Vincenzo Costanzo and colleagues now report that 'byproducts' of MRN's known task, the processing of DNA double strand breaks, function in inducing and sustaining ATM activation.
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Bacterial actin: architecture of the ParMRC plasmid DNA partitioning complex
Processive assembly of bacterial actin-like ParM filaments is crucial to separate replicated plasmids. Based on new results, Salje & Löwe propose an interesting model for bidirectional subunit incorporation by a formin-like assembly mechanism.
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Focus on quality control
This collection of eight review articles - Focus on Quality Control - highlights different aspects of cellular quality control and their potential relevance for human diseases. Topics include mitochondrial and ER quality control, protein folding and degradation; as well as quality control in RNA and DNA metabolism. The reviews will be printed in three subsequent regular issues of The EMBO Journal starting with the second issue in January 2008 (27.2). These online review articles include downloadable figures for teaching purposes and links to relevant research articles published recently in The EMBO Journal and other Nature Publishing Group titles.
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The EMBO Journal, EMBO reports provides sharply focused short papers and review articles in all areas of molecular biology. Its quality is reflected in its impact factor of 8.175*

*Journal Citation Reports, Thomson 2007

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