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The authors and editors assign up to two Subject Categories to each article upon acceptance of the manuscript. Further information   Articles top   Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling Tsuneo Ikenoue, Ken Inoki, Qian Yang, Xiaoming Zhou and Kun-Liang Guan The EMBO Journal (2008) 27, 1919–1931, doi:10.1038/emboj.2008.119 | Abstract | Full text | PDF (858K) | Supplementary Information | Published online: 19 June 2008 Subject Categories: Signal Transduction The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C Valeria Facchinetti, Weiming Ouyang, Hua Wei, Nelyn Soto, Adam Lazorchak, Christine Gould, Carolyn Lowry, Alexandra C Newton, Yuxin Mao, Robert Q Miao, William C Sessa, Jun Qin, Pumin Zhang, Bing Su and Estela Jacinto The EMBO Journal (2008) 27, 1932–1943, doi:10.1038/emboj.2008.120 | Abstract | Full text | PDF (975K) | Supplementary Information | Published online: 19 June 2008 Subject Categories: Signal Transduction Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme Yukimatsu Toh, Tomoyuki Numata, Kazunori Watanabe, Daijiro Takeshita, Osamu Nureki and Kozo Tomita The EMBO Journal (2008) 27, 1944–1952, doi:10.1038/emboj.2008.124 | Abstract | Full text | PDF (1481K) | Supplementary Information | Published online: 26 June 2008 Subject Categories: RNA | Proteins Mre11–Rad50–Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity EMBO Open Ali Jazayeri, Alessia Balestrini, Elizabeth Garner, James E Haber and Vincenzo Costanzo The EMBO Journal (2008) 27, 1953–1962, doi:10.1038/emboj.2008.128 | Abstract | Full text | PDF (515K) | Supplementary Information | Published online: 3 July 2008 Subject Categories: Genome Stability & Dynamics Induction of a pro-apoptotic ATM–NF-B pathway and its repression by ATR in response to replication stress Zhao-Hui Wu and Shigeki Miyamoto The EMBO Journal (2008) 27, 1963–1973, doi:10.1038/emboj.2008.127 | Abstract | Full text | PDF (1099K) | Supplementary Information | Published online: 26 June 2008 Subject Categories: Signal Transduction | Genome Stability & Dynamics Stress-protective signalling of prion protein is corrupted by scrapie prions Angelika S Rambold, Veronika Müller, Uri Ron, Nir Ben-Tal, Konstanze F Winklhofer and Jörg Tatzelt The EMBO Journal (2008) 27, 1974–1984, doi:10.1038/emboj.2008.122 | Abstract | Full text | PDF (1606K) | Supplementary Information | Published online: 19 June 2008 Subject Categories: Signal Transduction | Molecular Biology of Disease Small-molecule inhibition and activation-loop trans-phosphorylation of the IGF1 receptor Jinhua Wu, Wanqing Li, Barbara P Craddock, Kenneth W Foreman, Mark J Mulvihill, Qun-sheng Ji, W Todd Miller and Stevan R Hubbard The EMBO Journal (2008) 27, 1985–1994, doi:10.1038/emboj.2008.116 | Abstract | Full text | PDF (1315K) | Supplementary Information | Published online: 19 June 2008 Subject Categories: Signal Transduction | Structural Biology Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II Benjamin Stieglitz, Christine Bee, Daniel Schwarz, Özkan Yildiz, Anna Moshnikova, Andrei Khokhlatchev and Christian Herrmann The EMBO Journal (2008) 27, 1995–2005, doi:10.1038/emboj.2008.125 | Abstract | Full text | PDF (1953K) | Supplementary Information | Published online: 3 July 2008 Subject Categories: Signal Transduction | Structural Biology Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization Ekaterina P Lamber, Laurent Vanhille, Larissa C Textor, Galina S Kachalova, Michael H Sieweke and Matthias Wilmanns The EMBO Journal (2008) 27, 2006–2017, doi:10.1038/emboj.2008.117 | Abstract | Full text | PDF (1450K) | Supplementary Information | Published online: 19 June 2008 Subject Categories: Chromatin & Transcription | Structural Biology Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes Mugdha Bhati, Christopher Lee, Amy L Nancarrow, Mihwa Lee, Vanessa J Craig, Ingolf Bach, J Mitchell Guss, Joel P Mackay and Jacqueline M Matthews The EMBO Journal (2008) 27, 2018–2029, doi:10.1038/emboj.2008.123 | Abstract | Full text | PDF (1165K) | Supplementary Information | Published online: 26 June 2008 Subject Categories: Development | Structural Biology   Corrigendum top   Structure of Escherichia coli tyrosine kinase Etk reveals a novel activation mechanism Daniel C Lee, Jimin Zheng, Yi-Min She and Zongchao Jia The EMBO Journal (2008) 27, 2030, doi:10.1038/emboj.2008.130 | Abstract | Full text | PDF (301K) |

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